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Extensive historical use of castor oil for internal consumption and topical application has established it as safe. As an added measure of safety an investigation was conducted by feed studies in a national toxicology program of the US Department of Health and Human Services (National Institutes of Health). In 1990 the feed studies concluded there were "no significant adverse effects of castor oil administration in these Studies in rats or mice." Exposure to castor oil at dietary concentrations as high as 10% in 90-day studies did not affect survival or body weight gains (345). |
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